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Overview
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FK228; or FR901228; or Depsipeptide
Romidepsin is a potent and selective inhibitor of class I histone deacetylases (HDACs),IC50 = 36, 47, 510 and 14,000 nM for HDAC1, 2, 4 and HDAC6, respectively. Induces apoptosis in a variety of cell lines and displays antitumor activity in mouse models. Recently approved for clinical use in T-cell lymphoma.Please contact us at for specific academic pricing.
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- Properties
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Overview