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Overview
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Cryptotanshinone is one of several bioactive tanshinones extracted from the Chinese medicinal herb, Salvia mitiorrhiza. It exhibits a variety of bioactivity including antibacterial, antioxidant and anti-inflammatory effects, but has more recently gained interest for its promise in the field of cancer treatment.
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Background
Cryptotanshinone's antitumor activity comes from its ability to inhibit STAT3 phosphorylation, which downstream inhibits cell growth promoter cyclin D1, and interferes with apoptosis inhibitors survivin and Bcl-xL.
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- Properties
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Overview