Coenzyme A, Sodium salt

Coenzyme A, Sodium salt

Catalog Number:
CAD1547323COE
Mfr. No.:
A-17-10MG/25MG/50MG/100MG
Price:
$249
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      • Overview
        • Coenzyme A (CoA) is an indispensable and ubiquitous metabolic cofactor for all organisms. It is synthesized in an evolutionarily conserved pathway by enzymatic conjugation of cysteine, pantothenate (Vitamin B5), and ATP. This unique chemical structure allows CoA to employ its highly reactive thiol group for diverse biochemical reactions. CoA is involved in approximately 9% of all metabolic pathways, including the tricarboxylic acid (TCA) cycle, fatty acid regulation, amino acid synthesis, and lipid metabolism (Leonardi et al., 2005; Daugherty et al., 2002).

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      • Properties
        • Alternative Name
          CoA Na2
          CAS Number
          55672-92-9
          Molecular Formula
          C21H33N7O16P3S • xNa • yH2O
          Molecular Weight
          767.53 g/mol (anhydrous free acid basis)
          Appearance
          White to slight yellow
          Formulation
          Lyophilized powder
          Purity
          ≥ 98%
          Solubility
          Soluble in water
          Other Properties
          Origin: Biosynthetic
          Stability: ≥ 2 years
          Packaging: PP screw vials
          Storage
          -20°C in a cool and dry place
          Shipping
          Ambient temperature

          * For Research Use Only.

      • Applications
        • Application Description
          Coenzyme A Sodium Salt is widely used in metabolic research and biochemical studies due to its critical role in various enzymatic reactions and metabolic pathways. It is particularly valuable for investigating the mechanisms of energy production, lipid metabolism, and biosynthesis of key cellular components. Researchers utilize CoA Sodium Salt in studies related to cellular signaling, redox regulation, and metabolic diseases to understand better CoA's regulatory functions and its potential as a therapeutic target (Leonardi et al., 2005; Sibon & Strauss, 2016). Furthermore, its role in fatty acid oxidation and synthesis makes it a crucial reagent in developing treatments for metabolic disorders and understanding microbial metabolism (Spry et al., 2008).

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