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Overview
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Acetyl Coenzyme A (Acetyl-CoA) is a vital molecule in cellular metabolism, serving as a central intermediate in various biochemical processes. It is synthesized by the acetylation of Coenzyme A (CoA) through enzymatic reactions involving pyruvate dehydrogenase, β-oxidation of fatty acids, and amino acid catabolism. The unique structure of Acetyl-CoA, with its reactive acetyl group, allows it to participate in numerous biochemical reactions, including the tricarboxylic acid (TCA) cycle, fatty acid synthesis, and cholesterol metabolism, making it an essential cofactor in cellular energy production and biosynthetic pathways (Pietrocola et al., 2015; Shi & Tu, 2015).
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- Properties
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Overview