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Overview
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Acetyl Coenzyme A (Acetyl-CoA) is a central molecule in cellular metabolism, playing a pivotal role in energy production and biosynthesis. It is generated by the acetylation of Coenzyme A (CoA) through key enzymatic processes, including pyruvate decarboxylation by pyruvate dehydrogenase, fatty acid β-oxidation, and the catabolism of certain amino acids. Acetyl-CoA's reactive acetyl group enables its participation in various biochemical pathways, such as the tricarboxylic acid (TCA) cycle, fatty acid synthesis, and cholesterol metabolism, making it essential for cellular energy and biosynthetic processes (Pietrocola et al., 2015; Shi & Tu, 2015).
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- Properties
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Overview