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Overview
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Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl analogue (Chrysomycin A), albeit still a potent antitumor active and an inhibitor of the catalytic activity of human topoisomerase II.
Chrysomycin B is soluble in DMF and DMSO and is moderately soluble in methanol or ethanol.Please contact us at for specific academic pricing.
Background
The mechanism of action of chrysomycins is not fully understood; however, recent research suggests chrysomycins may act as photoactivated cross-linkers of DNA to histones.
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Overview
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