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Overview
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Chrysomycin A is the major analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex, and is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomycin A has a potent antibacterial, antifungal, antiviral and antitumor profile.
Chrysomycin A is soluble in DMF and DMSO and is moderately soluble in methanol or ethanol.Please contact us at for specific academic pricing.
Background
The mechanism of action of chrysomycins is not fully understood; however, recent research suggests chrysomycins may act as photoactivated cross-linkers of DNA to histones.
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Overview
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