Chemokine (C-X-C motif) Receptor 1 - ExpressMAX™ Human GPCR ORF Clones

Chemokine (C-X-C motif) Receptor 1 - ExpressMAX™ Human GPCR ORF Clones

Catalog Number:
MEV1268690CAN
Mfr. No.:
G0535-A; G0535-B; G0535-Plus
Price:
$375
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      • Overview
        • CXCR1 is a receptor for interleukine 8 (IL8) and it binds to IL8 with high affinity and transduces the signal through a G-protein activated second messenger systems. Knockout mice have inhibited embryonic oligodendrocyte precursor migration in developing spinal cord. In vitro and in mice has been shown that blocking CXCR1 inhibits some Human breast cancer stem cells. CXCR1 interacts with GNAI2.

          Includes:
          ExpressMAX™ GPCR ORF Clones (Cat. No. -A)
          – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
          ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
          – Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
          Mammalian Transfection Kits (Cat. No. – PLUS)
          – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
          – 0. 2 mL CANFAST™ Transfection Reagent.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Human GPCR ORF Clones
          Other Properties
          Plasmid size: 6762 bp
          Promoter: pEF1a
          ORF Sequence (GenBank based): NM_000634.2
          Protein Sequence (SwissProt): P25024
          Bacterial Selection Antibiotics: Ampicillin
          Mammalian Selection Antibiotic: Neomycin
          Alternative names: C-C, CD128, CD181 or CKR-1
          Storage
          ExpressMAX™ GPCR ORF Clones (-20 °C) and CANFAST™ (4 °C).

          * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.

      • Applications
        • Application Description
          Functional assays, as protein immobilization, cellular localization and other functional assays.
          High-throughput and large scale protein production and purification.
          Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

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