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Overview
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CXCR1 is a receptor for interleukine 8 (IL8) and it binds to IL8 with high affinity and transduces the signal through a G-protein activated second messenger systems. Knockout mice have inhibited embryonic oligodendrocyte precursor migration in developing spinal cord. In vitro and in mice has been shown that blocking CXCR1 inhibits some Human breast cancer stem cells. CXCR1 interacts with GNAI2.
Includes:
ExpressMAX™ GPCR ORF Clones (Cat. No. -A)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
Mammalian Transfection Kits (Cat. No. – PLUS)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0. 2 mL CANFAST™ Transfection Reagent.Please contact us at for specific academic pricing.
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- Properties
- Applications
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Overview