Chemokine (C-X-C motif) Receptor 2 - ExpressMAX™ Human GPCR ORF Clones

It is a receptor for Interleukin 8 (IL8). It binds to IL8 with high affinity and transduces the signal through a G-protein activated second messenger system. It also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity and has been shown to be a major component required for serum-dependent melanoma cell growth. It mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor.

Includes:
ExpressMAX™ GPCR ORF Clones (Cat. No. -A)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
Mammalian Transfection Kits (Cat. No. – PLUS)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0. 2 mL CANFAST™ Transfection Reagent.

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