Brefeldin A ReadyMade™ Solution

Brefeldin A ReadyMade™ Solution

Catalog Number:
M001555934TOK
Mfr. No.:
TOK-B098
Price:
$297
  • Size:
    0.2 mL
    Quantity:
    Add to Cart:
      • Overview
        • Brefeldin A ReadyMade™ Solution (BFA) is provided as a sterile-filtered solution of Brefeldin A formulated in DMSO at a concentration of 10 mg/ml. It has been filter-sterilized using a 0.22 μm filter. Brefeldin A is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. It is a bioactive small molecule which is an activator of the sphingomyelin cycle. Brefeldin A may be used to study protein and lipid transport between Golgi complex and the cell surface.

          Quantities above 1 gram is considered a Dangerous Good. This quantity may be subject to increased shipping fees. Please consult us for questions.

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      • Properties
        • CAS Number
          20350-15-6
          Molecular Formula
          C16H24O4
          Molecular Weight
          280.36
          Other Properties
          Mechanism of Action: Brefeldin A disrupts the structure/function of the Golgi apparatus via inhibition of protein transport from endoplasmic reticulum to the Golgi. The product inhibits the transport of sphingomyelin to the surface of mammalian cells.
          Storage
          -20°C

          * For Research Use Only,

      • Applications
        • Application Description
          Cancer Applications: Brefeldin A-mediated apoptosis has been observed in human tumor cells. The ester derivatives of Brefeldin A have anti-cancer properties.

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