BMP-2 derived peptide

BMP-2 derived peptide

Catalog Number:
P004516791LIF
Mfr. No.:
PEPTIDE-EI-030
Price:
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
        • Inhibits BMP-2 binding to BMP receptors type IA and type II.
          BMP-2 derived peptide, also known as bone morphogenetic protein 2 (BMP-2) derived peptide, corresponds to residues 73-92 of the knuckle epitope of BMP-2. BMP-2 derived peptide significantly inhibits the binding of recombinant human BMP-2 to both BMP receptors type IA and type II and also promotes the expression of osteocalcin mRNA and induces ectopic calcification in rat calf muscle. BMP-2 derived peptide may one of the receptor binding sites on BMP-2 and may stimulate bone precursor cells to induce calcification. The sequence lacking the GGC linker at the C teminal, BMP2pp is also available.

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      • Properties
        • Categories
          Peptides
          Alternative Name
          Bone morphogenetic protein 2 derived peptide
          Molecular Formula
          C104H176N26O32S
          Molecular Weight
          2334.76
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in water
          Other Properties
          Sequence: H-Lys-Ile-Pro-Lys-Ala-Ser-Ser-Val-Pro-Thr-Glu-Leu-Ser-Ala-Ile-Ser-Thr-Leu-Tyr-Leu-Gly-Gly-Cys-NH2,KIPKASSVPTELSAISTLYLGGC-NH2
          Modification: C terminal amide
          Storage
          Store desiccated, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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