Bischloroanthrabenzoxocinone

- Overview
  - Bischloroanthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC50 values of 11.4 and 35.3 µg/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. FASII is essential to bacterial cell viability and is a promising target for the development of novel antibiotics.
    
    Bischloroanthrabenzoxocinone is soluble in ethanol, methanol, DMF and DMSO.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    BABX has been shown to inhibit agonist binding to Liver X receptors (LXR). These receptors regulate the expression of the ABCA1 gene, which mediates the efflux of cholesterol from cells.
- Properties
  - CAS Number
    
    866022-28-8
    
    Molecular Formula
    
    C28H24O7Cl2
    
    Molecular Weight
    
    542.1
    
    Appearance
    
    Light orange residue
    
    Storage
    
    -20°C
    
    * For research use only