Biotinylated Human CXCR4 full length protein-synthetic nanodisc

Biotinylated Human CXCR4 full length protein-synthetic nanodisc

Catalog Number:
P001561646DIM
Mfr. No.:
FLP100074B
Price:
$1,114
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      • Overview

        • Target: CXCR4
          Tag: C-Flag&Avi Tag
          Synonyms: CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS1
          Protein Families: Transmembrane
          Protein Pathways: Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Leukocyte transendothelial migration

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          Background

          This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Biotinylated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length CXCR4 Protein has a MW of 44.5 kDa
          Expression system
          HEK293

          More Information

          UniProt
          P61073

          * For research use only.

    MSDS

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