Overview

Bestarose CL (Cross Link)-4B and Bestarose CL-6B are SEC resins obtained through emulsification, cleaning, cross-linking and screening on the basis of 4% and 6% agarose. Due to its wide fractionation range, it is used for the separation, purification and detection of polysaccharides, nucleic acids, viruses and other biological macro molecules. The resin also serves as base matrix for affinity, HIC, IEX resins. Bestarose CL-4B and Bestarose CL-6B are crosslinked on the basis of Bestarose 4B and Bestarose 6B via bi-functional crosslinker. While keeping the same fractionation range as Bestarose 4B and Bestarose 6B, the resins enjoys significantly improved physical and chemical properties, helping it withstand autoclaving at 121°C.

Product		Bestarose CL-4B	Bestarose CL-6B
Appearance		White slurry
Agarose concentration		4%	6%
Separation range	Linear numerator	30KD~5000KD	10KD~1000KD
	Globular molecule	60KD~20000KD	10KD~4000KD
Particle size⁺		45~165μm
Average particle size		~90μm
Max. operating flow velocity		25cm/h (BXK26/40,H=30cm,20°C,in water)	30cm/h (BXK26/40,H=30cm,20°C,in water)
Max. pressure		0.2bar	0.4bar
pH stability		3~13 (working),3~14 (CIP)
Chemical stability		Stable in common aqueous buffers: 4M urea, 70% ethanol
Storage++		2~30°C ,20% ethanol or 2% benzyl alcohol
Avoid		Freezing may damage the internal structure of the resin

+Particle size is normally distributed, and particles within this range account for more than 95% of the total.
++2% benzyl alcohol is only used for international transport or special requirements from customer.

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