BcMag™ One-Step Buccal Cell DNA Purification Kit

Large-scale genetic studies of the clinic and forensic sciences require efficient purification of sufficient quantities of inhibitors-free nucleic acids from collecting large amounts of different sample materials such as blood, saliva, buccal cell, etc. Among the samples, the buccal sample is often the preferred source since it is noninvasive to take and relatively easily collected. Moreover, samples can be ordered at home and mailed to the laboratory. Nevertheless, current DNA purification methods for the buccal cells suffer from one or more drawbacks, including low DNA yield, use of toxic organic solvents, time-consuming, laborious, or contamination with PCR inhibitors. To overcome these drawbacks, we developed a novel revolutionary one-step DNA purification system based on magnetic beads and negative chromatography, which combines DNA extraction with removing all the PCR inhibitors from the samples without performing DNA isolation and purification steps. BcMag™ One-Step Buccal Cell DNA Purification Kit allows rapid and efficient purification of genomic DNA from buccal swabs or pelleted cells from a mouthwash. It uses novel negative selection chromatography magnetic beads to quickly capture and remove the impurities such as PCR inhibitors from cell lysate, leaving the DNA untouched. It reduces the risk of DNA loss and carryover of extraction buffers from the traditional tedious bind-wash-elute procedure. The purification kit provides a fast and straightforward DNA extraction method with only one tube, no liquid transfer, and no requirement for carrier RNA. After preparing the lysates, Hundreds of samples can be processed in less than 30 minutes without using expensive equipment.

Please contact us at for specific academic pricing.