BcMag™ Hydrazide-terminated Magnetic Beads

BcMag™ Hydrazide-Terminated Magnetic Beads are uniform, silica-based superparamagnetic beads coated with high density hydrazide functional groups on the surface. The beads are used covalently couple aldehyde- or ketone-containing ligands such as antibody, lectin, glycoprotein, carbohydrates through the formation of stable hydrazine linkage. Such coupling method is a powerful way to immobilize proteins and leave critical active sites free.

• Covalently couples with high efficiency
• Ideal matrix for coupling polyclonal antibodies because beads only couple to Fc region, therefore both antigen-binding sites are free to interact with antigens.
• Stable covalent bond with minimal ligand leakage
• Produces reusable immunoaffinity matrices
• High efficiency in coupling Genomic DNA or RNA
• Immobilize 1-10 mg protein or 0.1-1 mg peptide/ml beads
• Applications: Purification for Antibodies, Proteins/Peptides, DNA/RNA; Cell sorting, Immunoprecipitation

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