Avermectin B1a monosaccharide

- Overview
  - Avermectin monosaccharide is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of avermectin. Avermectin monosaccharide is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. Despite the importance of avermectin as an anthelmintic in animal health, there are few published reports of the biological activity or the levels of avermectin monosaccharide in animals or in the environment.
    
    Avermectin monosaccharide is soluble in ethanol, methanol, DMF and DMSO.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Avermectins can modulate gamma-aminobutyric acid (GABA) chloride channels in vertebrate neurons.
- Properties
  - CAS Number
    
    71831-09-9
    
    Molecular Formula
    
    C41H60O11
    
    Molecular Weight
    
    728.9
    
    Appearance
    
    White solid
    
    Solubility
    
    soluble in ethanol, methanol, DMF and DMSO.
    
    Other Properties
    
    Source: semi-synthetic
    Purity Level: >95% by HPLC
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Insect Biology Applications: Electrophysiological findings by injection of E. elegans mRNA into Xenopus laevis oocytes indicated that Avermectins act on glutamate-gated chloride channels in nematodes.