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Overview
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Goat polyclonal antibody to TLR2. It is a 84 kDa type I transmembrane glycoprotein and a member of TLR family. It contains many leucine-rich repeat sequences and the intracellular Toll Interleukin Receptor Domain. TLR2 forms heterodimer with TLR1 and TLR6. It is expressed in peripheral blood leukocytes, and highly expressed in monocytes in bone marrow, lymph nodes, and spleen. It is also detectable in other tissues. This protein recognizes molecular patterns of bacteria, fungi, protozoan pathogens and stimulates pro-inflammatory cytokines as part of innate immunity.
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