Name: Anti-VEGFA antibody
Price: 224.00 USD

Overview
- VEGFA is a protein encoded by the VEGFA gene which is approximately 27, 1 kDa. VEGFA is freely secreted. It is involved in the response to elevated platelet cytosolic Ca2+, development VEGF signalling, CDK-mediated phosphorylation and removal of Cdc6 and RET signalling. It is a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Isoform VEGF189, VEGF165 and VEGF121 are widely expressed in human tissues. Mutations in the VEGFA gene may result in microvascular complications of diabetes. This gene is also upregulated in many known tumors. STJ96235 was affinity purified. This polyclonal antibody binds to VEGFA.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthesized peptide derived from human VEGF-A.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Vascular Endothelial Growth Factor A; Vegf-A; Vascular Permeability Factor; Vpf (Gene ID:7422; UniProt:P15692)
  
  * For research use only