Name: Anti-Thrombomodulin antibody
Price: 1476.00 USD

Overview
- Thrombomodulin is a transmembrane glycoprotein composed of 575 amino acids (molecular weight 75 kD) with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytiotrophoblasts ofhuman placenta also express thrombomodulin. Antithrombomodulin has demonstrated positivity inbenign vascular tumors such as hemangioma and most malignant vascular tumors (Kaposi's sarcomaand epitheliod hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker forlymphatic endothelial cells and their tumors. There has also been recent interest in the use of anti-thrombomodulin as an immunohiostochemical marker for mesothelial cells and malignantmesotheliomas. Anti-thrombomodulin is immunoexpressed in a variety of other tumors includingurothelial cell carcinomas.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1 kappa
  
  Reactivity
  
  human
  
  Clone
  
  1009
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Thrombomodulin; Tm; Fetomodulin; Cd Antigen Cd141 (Gene ID:7056; UniProt:P07204)
  
  * For research use only