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Overview
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Alpha-synuclein is a member of the synuclein family, which also includes beta-and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha-and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
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- Properties
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Overview
Immunofluorescence analysis of mouse brain using SNCA Rabbit pAb (STJ115317) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using SNCA Polyclonal Antibody (STJ115317) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 3min.
Immunohistochemistry of paraffin-embedded human gastric cancer using SNCA antibody (STJ115317) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using SNCA Polyclonal Antibody (STJ115317) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 1s.
Anti-SNCA antibody
Anti-SNCA antibody
Catalog Number:
A001022214STJ
Mfr. No.:
STJ115317
Price:
$297
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