Name: Anti-SKP1 antibody
Price: 297.00 USD

Overview
- This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant protein of human SKP1
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  S-Phase Kinase-Associated Protein 1; Cyclin-A/Cdk2-Associated Protein P19; P19a; Organ Of Corti Protein 2; Ocp-2; Organ Of Corti Protein II; Ocp-II; Rna Polymerase II Elongation Factor-Like Protein; SIII; Transcription Elongation Factor B Polypeptide 1-Like; P19skp1 (Gene ID:6500; UniProt:P63208)
  
  * For research use only