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Overview
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The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
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Overview
Immunofluorescence analysis of U2OS cells using SGCD antibody (STJ115314). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using SGCD antibody (STJ115314) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-SGCD antibody
Anti-SGCD antibody
Catalog Number:
A001022211STJ
Mfr. No.:
STJ115314
Price:
$297
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