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Overview
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This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Overview
Immunofluorescence analysis of HeLa cells using SDHA antibody (STJ25461). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human esophageal cancer using SDHA antibody (STJ25461) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using SDHA antibody (STJ25461) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver cancer using SDHA antibody (STJ25461) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using SDHA antibody (STJ25461) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 3s.
Anti-SDHA antibody
Anti-SDHA antibody
Catalog Number:
A001034959STJ
Mfr. No.:
STJ25461
Price:
$297
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