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Overview
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This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.
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Overview
Immunofluorescence analysis of NIH/3T3 cells using SELL antibody (STJ25469) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human gastric cancer using SELL antibody (STJ25469) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat testis using SELL antibody (STJ25469) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human tonsil using SELL antibody (STJ25469) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using SELL antibody (STJ25469) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-SELL antibody
Anti-SELL antibody
Catalog Number:
A001034964STJ
Mfr. No.:
STJ25469
Price:
$297
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