Anti-S-100 antibody - Amerigo Scientific

Overview
- S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes. Antibody to S100 stains Schwannomas, ependymomas, astrogliomas, almost all benign and malignant melanomas and their metastases. Ab‐1 is excellent for immunohistochemical staining of formalin‐fixed, paraffin embedded tissues. S100 protein is highly soluble and may be eluted from frozen tissue during staining tissues.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG2a kappa
  
  Reactivity
  
  human
  
  Clone
  
  4C4.9
  
  Immunogen
  
  Purified bovine brain S100 p
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Culture supernatant diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide.
  
  Storage
  
  Store at 2-8°C for up to 1 year
  
  Regulatory Status
  
  RUO
  
  * For research use only