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Overview
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This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
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- Properties
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Overview
Immunofluorescence analysis of C6 cells using CD133 antibody (STJ25156) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human prostate using CD133 antibody (STJ25156) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human lung using CD133 antibody (STJ25156) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using CD133 antibody (STJ25156) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 1s.
Anti-PROM1 antibody
Anti-PROM1 antibody
Catalog Number:
A001034781STJ
Mfr. No.:
STJ25156
Price:
$297
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