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Overview
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This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
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Overview
Immunofluorescence analysis of U2OS cells using PDK4 antibody (STJ24947). Blue: DAPI for nuclear staining.
Anti-PDK4 antibody
Anti-PDK4 antibody
Catalog Number:
A001034651STJ
Mfr. No.:
STJ24947
Price:
$297
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