Name: Anti-PDX1 antibody
Price: 297.00 USD

Overview
- The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PDX1 (NP_000200. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Pancreas/Duodenum Homeobox Protein 1; Pdx-1; Glucose-Sensitive Factor; Gsf; Insulin Promoter Factor 1; Ipf-1; Insulin Upstream Factor 1; Iuf-1; Islet/Duodenum Homeobox-1; Idx-1; Somatostatin-Transactivating Factor 1; Stf-1 (Gene ID:3651; UniProt:P52945)
  
  * For research use only