Name: Anti-PDIA3 antibody
Price: 297.00 USD

Overview
- This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 206-505 of human PDIA3 (NP_005304. 3).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Protein Disulfide-Isomerase A3; 58 Kda Glucose-Regulated Protein; 58 Kda Microsomal Protein; P58; Disulfide Isomerase Er-60; Endoplasmic Reticulum Resident Protein 57; Er Protein 57; Erp57; Endoplasmic Reticulum Resident Protein 60; Er Protein 60; Erp60 (Gene ID:2923; UniProt:P30101)
  
  * For research use only