Name: Anti-RBBP4 antibody
Price: 295.00 USD

Overview
- This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-425 of human RBBP4 (NP_005601. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Histone-Binding Protein Rbbp4; Chromatin Assembly Factor 1 Subunit C; Caf-1 Subunit C; Chromatin Assembly Factor I P48 Subunit; Caf-I 48 Kda Subunit; Caf-I P48; Nucleosome-Remodeling Factor Subunit Rbap48; Retinoblastoma-Binding Protein 4; Rbbp-4; Retinoblastoma-Binding Protein P48 (Gene ID:5928; UniProt:Q09028)
  
  * For research use only