Anti-PARP1 antibody

Anti-PARP1 antibody

Catalog Number:
A001037742STJ
Mfr. No.:
STJ29827
Price:
$297
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      • Overview
        • This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 81-390 of human PARP1 (NP_001609. 2).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Poly Adp-Ribose Polymerase 1; Parp-1; Adp-Ribosyltransferase Diphtheria Toxin-Like 1; Artd1; Dna Adp-Ribosyltransferase Parp1; Nad(+ Adp-Ribosyltransferase 1; Adprt 1; PolyAdp-Ribose Synthase 1; Protein Poly-Adp-Ribosyltransferase Parp1 (Gene ID:142; UniProt:P09874)

          * For research use only

      • Applications
        • Application
          WB; IHC
        • Application Dilutions
          WB 1:1000-1:3000
          IHC 1:50-1:200

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