Name: Anti-Parathyroid hormone antibody
Price: 337.00 USD

Overview
- PTH is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N‐terminal truncated fragments or C‐terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG2b kappa
  
  Reactivity
  
  human
  
  Clone
  
  ZM207
  
  Immunogen
  
  A synthetic peptide around aa 1‐34 of human mature‐PTH‐polypeptide; A recombinant fragment around aa 32‐115 of human mature PTH‐polypeptide (exact sequence is proprietary)
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Purified antibody diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide.
  
  Storage
  
  Store at 2-8°C for up to 1 year
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Parathyroid Hormone; Pth; Parathormone; Parathyrin (Gene ID:5741; UniProt:P01270)
  
  * For research use only