Name: Anti-Oct1 antibody
Price: 224.00 USD

Overview
- Oct1 is a protein encoded by the POU2F1 gene which is approximately 76, 4 kDa. Oct1 is localised to the nucleus. It is involved in cytokine signalling in the immune system, the BRCA1 pathway and PEDF induced signalling. It is a transcription factor that binds to the octamer motif (5-ATTTGCAT-3) and activates the promoters of the genes for some small nuclear RNAs and of genes such as those for histone H2B and immunoglobulins. It also modulates transcription transactivation by NR3C1, AR and PGR. Oct1 is expressed in the liver, lung, skin and cells of the nervous system. Mutations in the POU2F1 gene may result in primary amoebic meningoencephalitis. STJ96991 was developed from clone 7G1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous Oct1 protein.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human
  
  Clone
  
  7G1
  
  Immunogen
  
  Synthetic Peptide
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Pou Domain-Class 2-Transcription Factor 1; Nf-A1; Octamer-Binding Protein 1; Oct-1; Octamer-Binding Transcription Factor 1; Otf-1 (Gene ID:5451; UniProt:P14859)
  
  * For research use only