Anti-NFKBIZ antibody

Catalog Number:

A001020267STJ

Mfr. No.:

STJ112516

Price:

$297

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Overview
- This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NFKBIZ (NP_113607. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Nf-Kappa-B Inhibitor Zeta; I-Kappa-B-Zeta; Ikb-Zeta; Ikappabzeta; Il-1 Inducible Nuclear Ankyrin-Repeat Protein; Inap; Molecule Possessing Ankyrin Repeats Induced By Lipopolysaccharide; Mail (Gene ID:64332; UniProt:Q9BYH8)
  
  * For research use only