Western blot analysis of extracts of various cell lines, using ASIC2 antibody (STJ112520) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.

Anti-ASIC2 antibody

Catalog Number:

A001020271STJ

Mfr. No.:

STJ112520

Price:

$297

Size:

Quantity:

Add to Cart:

Add to Cart

Overview
- This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human ASIC2 (NP_001085. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Acid-Sensing Ion Channel 2; Asic2; Amiloride-Sensitive Brain Sodium Channel; Amiloride-Sensitive Cation Channel 1-Neuronal; Amiloride-Sensitive Cation Channel Neuronal 1; Brain Sodium Channel 1; Bnc1; Bnac1; Mammalian Degenerin Homolog; Mdeg (Gene ID:40; UniProt:Q16515)
  
  * For research use only