Name: Anti-NFKB2 antibody
Price: 297.00 USD

Overview
- This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 690-899 of human NFKB2 (NP_002493. 3).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Nuclear Factor Nf-Kappa-B P100 Subunit; Dna-Binding Factor Kbf2; H2tf1; Lymphocyte Translocation Chromosome 10 Protein; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 2; Oncogene Lyt-10; Lyt10 Cleaved Into-Nuclear Factor Nf-Kappa-B P52 Subunit (Gene ID:4791; UniProt:Q00653)
  
  * For research use only