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Overview
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This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2).
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- Properties
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Overview
Immunofluorescence analysis of 293T cells using NAT2 antibody (STJ114639) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human breast using NAT2 antibody (STJ114639) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat lung using NAT2 antibody (STJ114639) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using NAT2 antibody (STJ114639) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using NAT2 antibody (STJ114639) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 30s.
Anti-NAT2 antibody
Anti-NAT2 antibody
Catalog Number:
A001021587STJ
Mfr. No.:
STJ114639
Price:
$297
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