Anti-Myelin basic protein antibody

Anti-Myelin basic protein antibody

Catalog Number:
IGA1029521STJ
Mfr. No.:
STJ180336
Price:
$337
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      • Overview
        • Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30% of the total protein and about 10% of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin. MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin‐binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas.

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      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human
          Clone
          ZR109
          Immunogen
          Recombinant fragment (around aa 150‐250) of human MBP
          Conjugate
          Unconjugated
          Formulation
          Purified antibody diluted in 0.2% BSA and 15mM sodium azide.
          Storage
          Store at 2-8°C for up to 1 year
          Regulatory Status
          RUO
          Antigen
          Bone Marrow Proteoglycan; Bmpg; Proteoglycan 2 Cleaved Into-Eosinophil Granule Major Basic Protein; Embp; Mbp; Pregnancy-Associated Major Basic Protein (Gene ID:5553; UniProt:P13727)

          * For research use only

      • Applications
        • Application
          IHC (paraffin)
        • Application Dilutions
          IHC (paraffin) 1:100‐200

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