Anti-Mouse CD90 In Vivo Antibody - Low Endotoxin (T24/31)

Anti-Mouse CD90 In Vivo Antibody - Low Endotoxin (T24/31)

Catalog Number:
A001437241ICH
Mfr. No.:
ICH1064
Price:
$680
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      • Overview
        • Antigen Distribution: The CD90 Thy-1 antigen is present on thymocytes, peripheral T-cells and some intraepithelial T-lymphocytes of all mouse strains tested.
          Specificity: Anti-CD90 In Vivo Antibody - Low Endotoxin (T24/31) recognizes a non-polymorphic (Mr 25-30 kD) determinant on the Thy1.1 and Thy1.2 alloantigens.
          Isotype Control: Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)
          Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
          Aggregation: Aggregation level ≤ 5%

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          Background

          TCD90 or Thy1 is a 25-35 kDa GPI-anchored protein belonging to the Ig superfamily that is expressed by thymocytes, peripheral T cells, myoblasts, epidermal cells, and keratinocytes. The function of Thy1 is thought to play roles in regulation of cell adhesion, apoptosis, metastasis, inflammation, and fibrosis. Clone T24/31 antibody is useful for depletion of T lymphocytes.

      • Properties
        • Host
          rat
          Isotype
          IgG2b kappa
          Reactivity
          mouse
          Clone
          T24/31
          Immunogen
          Mouse Thy-1 protein
          Purification
          >95% by SDS-PAGE and HPLC
          Formulation
          0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
          Storage
          anti-CD90 In Vivo Antibody - Low Endotoxin (T24/31) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
          Molecular Weight
          1.0 - 5.0 mg/ml
          Regulatory Status
          Functional Assay: Anti Thy-1 is mitogenic for resting T-cells and induces IL-2 secretion from normal T-cells and T-cell hybridomas.
          Each investigator should determine their own optimal working dilution for specific applications.
          Antigen
          (Gene ID:Thy-1, Thy1)

          * Products are for research use only. Not for use in diagnostic or therapeutic procedures.

      • Applications
        • Application
          WB; Functional Assays; Flow Cytometry

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