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Overview
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MAP2 is a protein encoded by the MAP2 gene which is approximately 199, 5 kDa. MAP2 is localised to the cytoplasm. It is involved in the taxane pathway, neural stem cell differentiation pathways, the TGF-beta pathway and LKB1 signalling events. It is thought to be involved in microtubule assembly, which is an essential step in neurogenesis. MAP2 is expressed in the cells of the nervous system, intestine, heart, pancreas and liver. Mutations in the MAP2 gene may result in ganglioglioma. STJ96969 was developed from clone 7D4 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous MAP2 proteins.
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