Anti-LGALS3BP antibody

Catalog Number:

A001037041STJ

Mfr. No.:

STJ29009

Price:

$297

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Overview
- The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 306-585 of human LGALS3BP (NP_005558. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Galectin-3-Binding Protein; Basement Membrane Autoantigen P105; Lectin Galactoside-Binding Soluble 3-Binding Protein; Mac-2-Binding Protein; Mac2bp; Mac-2 Bp; Tumor-Associated Antigen 90k (Gene ID:3959; UniProt:Q08380)
  
  * For research use only