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Overview
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This gene encodes a member of the alpha/ beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15.
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- Properties
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Overview
Immunofluorescence analysis of U2OS cells using MEST antibody (STJ29011). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using MEST antibody (STJ29011) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.
Anti-MEST antibody
Anti-MEST antibody
Catalog Number:
A001037043STJ
Mfr. No.:
STJ29011
Price:
$297
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