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Overview
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This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human stomach using L2HGDH antibody (STJ110303) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using L2HGDH antibody (STJ110303) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using L2HGDH antibody (STJ110303) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-L2HGDH antibody
Anti-L2HGDH antibody
Catalog Number:
A001017148STJ
Mfr. No.:
STJ110303
Price:
$297
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