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Overview
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Cytokeratin 19 is a member of type I acidic subfamily of intermediate filaments. It is expressed in various different humantissuesexcept in liver. Keratin 19 is not expressed in hepatocytes, therefore, antibody to CK19 is useful inthe identification of liver metastasis.BA17reacts with the MCF‐7 cells, which are known to contain CK19. It shows no reaction with the cells lacking CK19 such as A431 and HeLa.In combinationwith HBME1, CK19 is useful in differentiating thyroid carcinoma from benign thyroid follicles.
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