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Overview
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Cytokeratin 20 (CK20) is a type‐1 keratin which is primarily expressed in gastric and intestinal epithelium, urothelium, and Merkel‐cells. CK20 is expressed in adenocarcinomas of the colon, stomach, pancreas and the bile system. CK20 is also present in mucinous ovarian tumors, transitional‐cell and Merkel‐cell carcinomas. Notably, the squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non‐mucinous tumors of the ovary, and small cell carcinomas lack in CK20.
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Overview