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Overview
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Cytokeratin 18 (CK18), which belongs to the type A (acidic) subfamily of low molecular weight keratins exists in combination with CK8. It was reported that tissues from gastrointestinal tract are positive for both CK8 and CK18 but do not contain CK14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for CK18. DC10 recognizes a variety of simple epithelia including glandular epithelium but not stratified squamous epithelia.
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