Name: Anti-Inflammatory Peptide 1
Price: 196.00 USD

- Overview
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    Background
    
    Anti-Inflammatory Peptide 1 (C45H82N12O14S2), with the sequence H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH, belongs to the group of synthetic oligopeptides corresponding to a region of high amino-acid sequence similarity between uteroglobin and lipocortin I. The name 'antiflammins' is proposed for those peptides, which are valuable models for the development of novel anti-inflammatory agents of therapeutic importance. Anti-inflammatory peptide 1 possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammation and pain at certain bodily sites.
    
    1. Argiolas A, Pisano JJ (November 1983). "Facilitation of phospholipase A2 activity by mastoparans, a new class of mast cell degranulating peptides from wasp venom". J. Biol. Chem. 258 (22): 13697–702.
- Properties
  - Alternative Name
    
    H2N-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH; Anti-Inflammatory Peptide 1
    
    CAS Number
    
    118850-71-8
    
    Molecular Formula
    
    C45H82N12O14S2
    
    Molecular Weight
    
    1079.33
    
    Appearance
    
    A solid
    
    Purity
    
    99.99%
    
    Solubility
    
    ≥107.9 mg/mL in DMSO; insoluble in EtOH; ≥21.13 mg/mL in H2O
    
    Storage
    
    Store at -20°C
    
    * For Research Use Only