-
-
Overview
-
The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.
Please contact us at for specific academic pricing.
-
- Properties
- Applications
-
Overview
Immunohistochemistry of paraffin-embedded human uterine cancer using HUS1 antibody (STJ115873) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using HUS1 antibody (STJ115873) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat liver using HUS1 antibody (STJ115873) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using HUS1 antibody (STJ115873) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of mouse kidney, using HUS1 antibody (STJ115873) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 180s.
Anti-HUS1 antibody
Anti-HUS1 antibody
Catalog Number:
A001022752STJ
Mfr. No.:
STJ115873
Price:
$297
Size:
Quantity:
Add to Cart:
.