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Overview
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The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1. 6 kb and a protein product with a molecular weight of about 35 kDa.
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- Properties
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Overview
Western blot analysis of extracts from normal (control) and ANXA5 knockout (KO) 293T cells, using ANXA5 antibody (STJ22620) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 1s.
Immunofluorescence analysis of HeLa cells using [KO Validated] ANXA5 Rabbit pAb (STJ22620) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using ANXA5 antibody (STJ22620) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Anti-ANXA5 antibody
Anti-ANXA5 antibody
Catalog Number:
A001033318STJ
Mfr. No.:
STJ22620
Price:
$295
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